TNFSF4 Antikörper (Middle Region)

Produktnummer ABIN951249

Produktdetails anti-TNFSF4 Antikörper

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Bindungsspezifität: AA 98-126, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects CD252 / TNFSF4 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human TNFSF4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu TNFSF4

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Andere Bezeichnung: CD252 / TNFSF4 (TNFSF4 Produkte)

Synonyme: TNFSF4 antikoerper, OX40L antikoerper, TNFRSF4 antikoerper, CD134L antikoerper, CD252 antikoerper, GP34 antikoerper, OX-40L antikoerper, OX4OL antikoerper, TXGP1 antikoerper, Ath-1 antikoerper, Ath1 antikoerper, Ox40l antikoerper, Txgp1l antikoerper, gp34 antikoerper, TNF superfamily member 4 antikoerper, tumor necrosis factor (ligand) superfamily, member 4 antikoerper, TNFSF4 antikoerper, Tnfsf4 antikoerper

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.Synonyms: Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, Tumor necrosis factor ligand superfamily member 4

Gen-ID: 7292

NCBI Accession: NP_003317

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints