ADRBK2 Antikörper (N-Term)

Produktnummer ABIN950649

Produktdetails anti-ADRBK2 Antikörper

Target: ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))

Bindungsspezifität: AA 36-65, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRBK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Beta-ARK-2.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 36~65 amino acids from the N-terminal region of human ADRBK2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-ADRBK2 Antikörper (ABIN950649)

Rao, Rapoport, Kim: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, (2009) (PubMed).

Details zu ADRBK2

Target: ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))

Andere Bezeichnung: beta-ARK-2 / ADRBK2 (ADRBK2 Produkte)

Synonyme: bark2 antikoerper, grk3 antikoerper, 4833444A01Rik antikoerper, AI851927 antikoerper, AW551196 antikoerper, Adrbk-2 antikoerper, Bark-2 antikoerper, GRK3 antikoerper, BARK2 antikoerper, Grk3 antikoerper, si:dz221d18.1 antikoerper, G protein-coupled receptor kinase 3 antikoerper, GRK3 antikoerper, grk3 antikoerper, Grk3 antikoerper

Hintergrund: ADRBK2 is the beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85 % amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95 % similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.Synonyms: BARK2, Beta-adrenergic receptor kinase 2, G-protein-coupled receptor kinase 3, GRK3

Gen-ID: 157

NCBI Accession: NP_005151

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling