B3GALT5 Antikörper (N-Term)

Produktnummer ABIN950586

Produktdetails anti-B3GALT5 Antikörper

Target: B3GALT5 (UDP-Gal:betaGlcNAc beta 1,3-Galactosyltransferase, Polypeptide 5 (B3GALT5))

Bindungsspezifität: AA 64-91, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser B3GALT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to B3GALT5.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human B3GALT5

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu B3GALT5

Target: B3GALT5 (UDP-Gal:betaGlcNAc beta 1,3-Galactosyltransferase, Polypeptide 5 (B3GALT5))

Andere Bezeichnung: B3GALT5 (B3GALT5 Produkte)

Synonyme: B3GALT5 antikoerper, B3GalT-V antikoerper, B3GalTx antikoerper, B3T5 antikoerper, GLCT5 antikoerper, beta-1,3-GalTase 5 antikoerper, beta-3-Gx-T5 antikoerper, beta3Gal-T5 antikoerper, 1190002B21Rik antikoerper, AU045265 antikoerper, b3Galt-V antikoerper, b3Gal-T5 antikoerper, Beta-1,3-galactosyltransferase 5 antikoerper, beta-1,3-galactosyltransferase 5 antikoerper, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 antikoerper, B3galt5 antikoerper, B3GALT5 antikoerper

Hintergrund: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes the most probable candidate for synthesis of the type 1 Lewis antigens which are frequently found to be elevated in gastrointestinal and pancreatic cancers. The encoded protein is inactive with N-linked glycoproteins and functions in mucin glycosylation. Five transcript variants have been described which differ in the 5' UTR. All transcript variants encode an identical protein.Synonyms: 3-GalTase 5, 3-galactosyltransferase 5, Beta-1, Beta-1, Beta-3-Gx-T5, Beta3Gal-T5, UDP-Gal:beta-GlcNAc beta-1, UDP-galactose:beta-N-acetylglucosamine beta-1, b3Gal-T5

Gen-ID: 10317

NCBI Accession: NP_006048