ATP6V1B1 Antikörper (Middle Region)

Produktnummer ABIN950569

Produktdetails anti-ATP6V1B1 Antikörper

Target: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Bindungsspezifität: AA 291-318, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ATP6V1B1.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human ATP6V1B1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ATP6V1B1

Target: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Andere Bezeichnung: ATP6V1B1 (ATP6V1B1 Produkte)

Synonyme: ATP6B1 antikoerper, RTA1B antikoerper, VATB antikoerper, VMA2 antikoerper, VPP3 antikoerper, AW208839 antikoerper, Atp6b1 antikoerper, D630003L15 antikoerper, D630030L16Rik antikoerper, D630039P21Rik antikoerper, Vpp-3 antikoerper, Vpp3 antikoerper, ATPase H+ transporting V1 subunit B1 antikoerper, ATPase, H+ transporting, lysosomal V1 subunit B1 antikoerper, ATP6V1B1 antikoerper, Atp6v1b1 antikoerper

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq].Synonyms: ATP6B1, Endomembrane proton pump 58 kDa subunit, V-ATPase subunit B 1, V-type proton ATPase subunit B, VATB, VPP3, Vacuolar proton pump subunit B 1, kidney isoform

Gen-ID: 525

NCBI Accession: NP_001683

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport