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ATP6V0B Antikörper (Middle Region)

ATP6V0B Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN950566
  • Target Alle ATP6V0B Antikörper anzeigen
    ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    AA 111-139, Middle Region
    Reaktivität
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ATP6V0B Antikörper ist unkonjugiert
    Applikation
    • 16
    • 12
    • 12
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to ATP6V0B.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 111-139 amino acids from the Central region of human ATP6V0B
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ATP6V0B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) sodium azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))
    Andere Bezeichnung
    ATP6V0B (ATP6V0B Produkte)
    Synonyme
    ATP6F antikoerper, HATPL antikoerper, VMA16 antikoerper, 2310024H13Rik antikoerper, Atp6f antikoerper, ATPase H+ transporting V0 subunit b antikoerper, ATPase, H+ transporting, lysosomal V0 subunit B antikoerper, ATPase H+ transporting V0 subunit B antikoerper, ATP6V0B antikoerper, Atp6v0b antikoerper
    Hintergrund
    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.Synonyms: ATP6F, HATPL, V-ATPase 21 kDa proteolipid subunit, V-type proton ATPase 21 kDa proteolipid subunit, Vacuolar proton pump 21 kDa proteolipid subunit
    Gen-ID
    533
    NCBI Accession
    NP_001034546
    Pathways
    Transition Metal Ion Homeostasis, Proton Transport
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