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NAE1 Antikörper (Middle Region)
NAE1
Reaktivität: Human
WB, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-NAE1 Antikörper
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Target
Alle NAE1 Antikörper anzeigen
NAE1
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
Bindungsspezifität
Alle Epitope für NAE1 Antikörper
AA 171-200, Middle Region
Reaktivität
Alle Reaktivitäten für NAE1 Antikörper
Human
Wirt
Alle Wirte für NAE1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für NAE1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für NAE1 Antikörper
Dieser NAE1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für NAE1 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody recognizes Human APPBP1 (Center).
Aufreinigung
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human APPBP1 Genename: NAE1
Isotyp
Ig Fraction
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu NAE1
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Target
NAE1
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
Andere Bezeichnung
APPBP1 (NAE1 Produkte )
Synonyme
APPBP1 antikoerper, CG7828 antikoerper, Dmel\\CG7828 antikoerper, anon-WO0140519.225 antikoerper, dAPP-BP1 antikoerper, dAPPBP1 antikoerper, A-116A10.1 antikoerper, ula-1 antikoerper, Appbp1 antikoerper, 59kDa antikoerper, appbp1 antikoerper, zgc:66148 antikoerper, beta-Amyloid precursor protein binding protein 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 S homeolog antikoerper, nedd8 activating enzyme E1 subunit 1 antikoerper, NEDD8-activating enzyme E1 regulatory subunit antikoerper, APP-BP1 antikoerper, NAE1 antikoerper, Nae1 antikoerper, nae1.S antikoerper, nae1 antikoerper, ula-1 antikoerper
Hintergrund
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.Synonyms: Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, HPP1, NAE1
Molekulargewicht
60246 Da
Gen-ID
8883
NCBI Accession
NP_001018169
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