PRKAG1 Antikörper (N-Term)

Produktnummer ABIN950401

Produktdetails anti-PRKAG1 Antikörper

Target: PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Bindungsspezifität: AA 5-33, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to PRKAG1.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human PRKAG1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PRKAG1

Target: PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Andere Bezeichnung: AMPK gamma-1 Chain / AMPKg (PRKAG1 Produkte)

Synonyme: MGC68503 antikoerper, zgc:63896 antikoerper, wu:fa94d09 antikoerper, wu:fd12h04 antikoerper, AMPKG antikoerper, Prkaac antikoerper, Prkga1 antikoerper, AA571379 antikoerper, BB036179 antikoerper, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 1 non-catalytic subunit antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 1 antikoerper, prkag1.S antikoerper, prkag1 antikoerper, PRKAG1 antikoerper, Prkag1 antikoerper

Hintergrund: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Synonyms: 5'-AMP-activated protein kinase subunit gamma-1, PRKAG1

Molekulargewicht: 37579 Da

Gen-ID: 5571

NCBI Accession: NP_001193638

Pathways: AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effekt