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CD235ab Antikörper (N-Term)

CD235a + CD235b Reaktivität: Human FACS, IHC (fro), IHC (p), AGG Wirt: Maus Monoclonal HIR2 unconjugated
Produktnummer ABIN94041
  • Target Alle CD235ab (CD235a + CD235b) Produkte
    CD235ab (CD235a + CD235b) (Glycophorin A + B (CD235a + CD235b))
    Bindungsspezifität
    N-Term
    Reaktivität
    Human
    Wirt
    • 16
    • 1
    Maus
    Klonalität
    • 16
    • 1
    Monoklonal
    Konjugat
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD235ab Antikörper ist unkonjugiert
    Applikation
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Aggregation (AGG)
    Spezifität
    The mouse monoclonal antibody HIR2 recognizes an epitope within the N-terminal (extracellular) portion of CD235a (glycophorin A) and CD235b (glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Synthetic peptide (Human, N-terminal)
    Klon
    HIR2
    Isotyp
    IgG2b
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CD235ab (CD235a + CD235b) (Glycophorin A + B (CD235a + CD235b))
    Andere Bezeichnung
    CD235ab (CD235a + CD235b Produkte)
    Hintergrund
    CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A/B, GYPA/B, GPA/B, PAS-2/3, Sialoglycoprotein alpha/beta, GPSAT, GPErik, MSN blood group
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