Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD14 Antikörper

CD14 Reaktivität: Human FACS, ELISA, IHC (p) Wirt: Maus Monoclonal B-A8 unconjugated
Produktnummer ABIN93977
  • Target Alle CD14 Antikörper anzeigen
    CD14
    Reaktivität
    • 268
    • 55
    • 32
    • 30
    • 29
    • 28
    • 25
    • 24
    • 24
    • 18
    • 17
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 224
    • 64
    • 25
    • 3
    • 1
    Maus
    Klonalität
    • 253
    • 64
    Monoklonal
    Konjugat
    • 128
    • 30
    • 24
    • 18
    • 15
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD14 Antikörper ist unkonjugiert
    Applikation
    • 223
    • 104
    • 63
    • 59
    • 54
    • 50
    • 22
    • 21
    • 21
    • 14
    • 14
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    The mouse monoclonal antibody B-A8 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked extracellular membrane glycoprotein expressed on the surface of monocytes, macrophages and weakly on granulocytes, also expressed by most tissue macrophages.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human monocytes
    Klon
    B-A8
    Isotyp
    IgG1
    Top Product
    Discover our top product CD14 Primärantikörper
  • Applikationshinweise
    ELISA: The antibody B-A8 has been tested as the capture antibody in a sandwich ELISA for analysis of human CD14 in combination with antibody MEM-18 (cat. no. 1B-212-C100). Flow cytometry: recommended dilution: 1 μg/mL, Immunohistochemistry (paraffin sections): recommended dilution: 2-10 μg/mL, positive tissue: PML brain sections, positive staining on human PML brain sections was mainly observed on monocytes in the lumenal side of brain blood vessels, and on some perivascular cells adjacent to medium-sized vessels. Heat retrieval of antigen is recommeded.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Yates, Rovis, Mitchell, Afzali, Tsang, Garin, Lechler, Lombardi, Garden: "The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro." in: International immunology, Vol. 19, Issue 6, pp. 785-99, (2007) (PubMed).

    Kuusniemi, Lapatto, Holmberg, Karikoski, Rapola, Jalanko: "Kidneys with heavy proteinuria show fibrosis, inflammation, and oxidative stress, but no tubular phenotypic change." in: Kidney international, Vol. 68, Issue 1, pp. 121-32, (2005) (PubMed).

    Matasić, Dietz, Vuk-Pavlović: "Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells." in: Journal of leukocyte biology, Vol. 66, Issue 6, pp. 909-14, (2000) (PubMed).

    Goyert, Ferrero, Rettig, Yenamandra, Obata, Le Beau: "The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors." in: Science (New York, N.Y.), Vol. 239, Issue 4839, pp. 497-500, (1988) (PubMed).

  • Target
    CD14
    Andere Bezeichnung
    CD14 (CD14 Produkte)
    Synonyme
    CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
    Hintergrund
    CD14 Molecule,CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where it serves as a multifunctional lipopolysaccharide receptor. It is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.,LPS-receptor, LPSR, MCLR
    Gen-ID
    929
    UniProt
    P08571
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Sie sind hier:
Kundenservice