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ERBB3 Antikörper (AA 1175-1275)
ERBB3
Reaktivität: Human
WB, ELISA, IHC
Wirt: Maus
Monoclonal
3F10F6
unconjugated
Produktdetails anti-ERBB3 Antikörper
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Target
Alle ERBB3 Antikörper anzeigen
ERBB3
(Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
Bindungsspezifität
Alle Epitope für ERBB3 Antikörper
AA 1175-1275
Reaktivität
Alle Reaktivitäten für ERBB3 Antikörper
Human
Wirt
Alle Wirte für ERBB3 Antikörper
Maus
Klonalität
Alle Klonalitäten für ERBB3 Antikörper
Monoklonal
Konjugat
Alle Konjugate für ERBB3 Antikörper
Dieser ERBB3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ERBB3 Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Immunogen
ERBB3 antibody was raised in Mouse using a purified recombinant fragment of ERBB3(aa1175-1275) expressed in E. coli as the immunogen.
Klon
3F10F6
Isotyp
IgG1
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Discover our top product ERBB3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Details zu ERBB3
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Target
ERBB3
(Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
Andere Bezeichnung
ERBB3 (ERBB3 Produkte )
Synonyme
ErbB-3 antikoerper, HER3 antikoerper, LCCS2 antikoerper, MDA-BF-1 antikoerper, c-erbB-3 antikoerper, c-erbB3 antikoerper, erbB3-S antikoerper, p180-ErbB3 antikoerper, p45-sErbB3 antikoerper, p85-sErbB3 antikoerper, ERBB3 antikoerper, C76256 antikoerper, Erbb-3 antikoerper, Erbb3r antikoerper, Her3 antikoerper, nuc-ErbB3 antikoerper, erb-b2 receptor tyrosine kinase 3 antikoerper, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antikoerper, ERBB3 antikoerper, Erbb3 antikoerper
Hintergrund
ERBB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Synonyms: Monoclonal ERBB3 antibody, Anti-ERBB3 antibody, V-erb-b2 antibody, Erythroblastic leukemia viral oncogene homolog 3 antibody.
Pathways
RTK Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung
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