PRKAR1A Antikörper

Produktnummer ABIN931105

Produktdetails anti-PRKAR1A Antikörper

Target: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRKAR1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: PRKAR1 A antibody was raised in mouse using recombinant Human Protein Kinase, Camp-Dependent, Regulatory, Type I, Alpha (Tissue Specific Extinguisher 1) (Prkar1 )

Klon: 3546C2a

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: PRKAR1 A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu PRKAR1A

Target: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Andere Bezeichnung: PRKAR1A (PRKAR1A Produkte)

Synonyme: ACRDYS1 antikoerper, ADOHR antikoerper, CAR antikoerper, CNC antikoerper, CNC1 antikoerper, PKR1 antikoerper, PPNAD1 antikoerper, PRKAR1 antikoerper, TSE1 antikoerper, 1300018C22Rik antikoerper, RIalpha antikoerper, Tse-1 antikoerper, Tse1 antikoerper, RIIA antikoerper, prkar1a antikoerper, zgc:92515 antikoerper, im:7047729 antikoerper, cnc1 antikoerper, pkr1 antikoerper, ppnad1 antikoerper, prkar1 antikoerper, tse1 antikoerper, protein kinase cAMP-dependent type I regulatory subunit alpha antikoerper, protein kinase, cAMP dependent regulatory, type I, alpha antikoerper, protein kinase cAMP-dependent type 1 regulatory subunit alpha antikoerper, protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a antikoerper, cAMP-dependent protein kinase type I-alpha regulatory subunit pseudogene antikoerper, protein kinase cAMP-dependent type I regulatory subunit alpha S homeolog antikoerper, PRKAR1A antikoerper, Prkar1a antikoerper, prkar1aa antikoerper, LOC707275 antikoerper, prkar1a.S antikoerper

Hintergrund: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMPdependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Synonyms: Monoclonal PRKAR1A antibody, Anti-PRKAR1A antibody, Protein kinase cAMP dependent regulatory type I alpha antibody, CAR antibody, CNC antibody, CNC1 antibody, PKR1 antibody, TSE1 antibody, PPNAD1 antibody, PRKAR1 antibody, MGC17251 antibody, DKFZp779L0468 antibody.

Pathways: Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma