CTSC Antikörper (Middle Region)

Produktnummer ABIN929442

Produktdetails anti-CTSC Antikörper

Target: CTSC (Cathepsin C (CTSC))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTSC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: CTSC antibody was raised in rabbit using the middle region of CTSC as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CTSC Blocking Peptide, catalog no. 33R-10021, is also available for use as a blocking control in assays to test for specificity of this CTSC antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CTSC

Target: CTSC (Cathepsin C (CTSC))

Andere Bezeichnung: CTSC (CTSC Produkte)

Synonyme: CPPI antikoerper, DPP-I antikoerper, DPP1 antikoerper, DPPI antikoerper, HMS antikoerper, JP antikoerper, JPD antikoerper, PALS antikoerper, PDON1 antikoerper, PLS antikoerper, MGC69126 antikoerper, MGC107782 antikoerper, AI047818 antikoerper, CATC antikoerper, cb912 antikoerper, ik:tdsubc_1h2 antikoerper, sb:cb146 antikoerper, wu:fb34g12 antikoerper, wu:fj58d01 antikoerper, cathepsin C antikoerper, cathepsin C L homeolog antikoerper, cathepsin CPC1 antikoerper, CTSC antikoerper, ctsc.L antikoerper, ctsc antikoerper, TP03_0357 antikoerper, CMU_003360 antikoerper, CPC1 antikoerper, NAEGRDRAFT_80477 antikoerper, NAEGRDRAFT_37577 antikoerper, Ctsc antikoerper, Smp_183330 antikoerper

Hintergrund: CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Synonyms: Polyclonal CTSC antibody, Anti-CTSC antibody, cathepsin C antibody, CPPI antibody, DPP1 antibody, DPPI antibody, HMS antibody, JP antibody, JPD antibody, PALS antibody, PLS antibody.