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USP20 Antikörper (Middle Region)

USP20 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN929196
  • Target Alle USP20 Antikörper anzeigen
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 42
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 4
    • 1
    Kaninchen
    Klonalität
    • 42
    • 1
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 4
    • 4
    • 4
    Dieser USP20 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 26
    • 17
    • 4
    • 4
    Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    USP20 antibody was raised in rabbit using the middle region of USP20 as the immunogen
    Top Product
    Discover our top product USP20 Primärantikörper
  • Applikationshinweise
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    Andere Bezeichnung
    USP20 (USP20 Produkte)
    Synonyme
    USP20 antikoerper, vdu2 antikoerper, lsfr3a antikoerper, LSFR3A antikoerper, VDU2 antikoerper, hVDU2 antikoerper, 1700055M05Rik antikoerper, AI467231 antikoerper, Vdu2 antikoerper, im:7151955 antikoerper, zgc:63661 antikoerper, universal stress protein antikoerper, ubiquitin specific peptidase 20 antikoerper, ubiquitin specific peptidase 20 L homeolog antikoerper, RR_RS15875 antikoerper, USP20 antikoerper, usp20 antikoerper, Usp20 antikoerper, usp20.L antikoerper
    Hintergrund
    USP20 is a deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling.USP20 acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). USP20 plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Synonyms: Polyclonal USP20 antibody, Anti-USP20 antibody, ubiquitin specific peptidase 20 antibody, KIAA1003 antibody, LSFR3A antibody, VDU2 antibody.
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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