USP8 Antikörper (C-Term)

Produktnummer ABIN929183

Produktdetails anti-USP8 Antikörper

Target: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: USP8 antibody was raised in rabbit using the C terminal of USP8 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

USP8 Blocking Peptide, catalog no. 33R-2843, is also available for use as a blocking control in assays to test for specificity of this USP8 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu USP8

Target: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Andere Bezeichnung: USP8 (USP8 Produkte)

Synonyme: HumORF8 antikoerper, UBPY antikoerper, AI574262 antikoerper, AW557536 antikoerper, Ubpy antikoerper, mKIAA0055 antikoerper, ubiquitin carboxyl-terminal hydrolase 8 antikoerper, ubiquitin specific peptidase 8 antikoerper, LOC9310109 antikoerper, MGYG_00369 antikoerper, USP8 antikoerper, Usp8 antikoerper

Hintergrund: USP8 is a hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. USP8 catalytic activity is enhanced in the M phase. USP8 is involved in cell proliferation. USP8 is required to enter into S phase in response to serum stimulation. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. USP8 probably regulates the stability of STAM2 and RASGRF1. USP8 regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. Synonyms: Polyclonal USP8 antibody, Anti-USP8 antibody, ubiquitin specific peptidase 8 antibody, FLJ34456 antibody, HumORF8 antibody, KIAA0055 antibody, MGC129718 antibody, UBPY antibody.