PSMF1 Antikörper (Middle Region)

Produktnummer ABIN929149

Produktdetails anti-PSMF1 Antikörper

Target: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: PSMF1 antibody was raised in rabbit using the middle region of PSMF1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PSMF1 Blocking Peptide, catalog no. 33R-2238, is also available for use as a blocking control in assays to test for specificity of this PSMF1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PSMF1

Target: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Andere Bezeichnung: PSMF1 (PSMF1 Produkte)

Synonyme: PI31 antikoerper, AW048666 antikoerper, BC012260 antikoerper, zgc:92785 antikoerper, proteasome inhibitor subunit 1 antikoerper, proteasome (prosome, macropain) inhibitor subunit 1 antikoerper, PSMF1 antikoerper, Psmf1 antikoerper, psmf1 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. Synonyms: Polyclonal PSMF1 antibody, Anti-PSMF1 antibody, proteasome, prosome, macropain inhibitor subunit 1, PI31 antibody, PI31 antibody.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA