PSME2 Antikörper (Middle Region)

Produktnummer ABIN928858

Produktdetails anti-PSME2 Antikörper

Target: PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSME2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: PSME2 antibody was raised in rabbit using the middle region of PSME2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PSME2 Blocking Peptide, catalog no. 33R-7527, is also available for use as a blocking control in assays to test for specificity of this PSME2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PSME2

Target: PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))

Andere Bezeichnung: PSME2 (PSME2 Produkte)

Synonyme: unp309 antikoerper, PA28B antikoerper, PA28beta antikoerper, REGbeta antikoerper, AA589371 antikoerper, AI788882 antikoerper, PA28b antikoerper, proteasome activator subunit 2 antikoerper, proteasome (prosome, macropain) activator subunit 2 (PA28 beta) antikoerper, psme2 antikoerper, PSME2 antikoerper, Psme2 antikoerper

Hintergrund: An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. Synonyms: Polyclonal PSME2 antibody, Anti-PSME2 antibody, proteasome, prosome, macropain activator subunit 2, PA28 beta antibody, PA28B antibody, PA28beta antibody, REGbeta antibody.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA