PPP2R2D Antikörper (C-Term)

Produktnummer ABIN928830

Produktdetails anti-PPP2R2D Antikörper

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Ppp2 r2 antibody was raised in rabbit using the C terminal of Ppp2 2 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Ppp2r2d Blocking Peptide, catalog no. 33R-8132, is also available for use as a blocking control in assays to test for specificity of this Ppp2r2d antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PPP2R2D

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Andere Bezeichnung: Ppp2r2d (PPP2R2D Produkte)

Synonyme: 1300017E19Rik antikoerper, D7Ertd753e antikoerper, MDS026 antikoerper, protein phosphatase 2, regulatory subunit B, delta antikoerper, protein phosphatase 2 regulatory subunit Bdelta antikoerper, protein phosphatase 2 regulatory subunit B, delta S homeolog antikoerper, Ppp2r2d antikoerper, PPP2R2D antikoerper, ppp2r2d.S antikoerper

Hintergrund: Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment. Synonyms: Polyclonal Ppp2r2d antibody, Anti-Ppp2r2d antibody, protein phosphatase 2, regulatory subunit B, delta isoform antibody, 1300017E19Rik antibody, D7Ertd753e antibody, MDS026 antibody.