Frataxin Antikörper (Middle Region)

Produktnummer ABIN928236

Produktdetails anti-Frataxin Antikörper

Target: Frataxin (FXN)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Frataxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Fxn antibody was raised in rabbit using the middle region of Fxn as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Fxn Blocking Peptide, catalog no. 33R-9164, is also available for use as a blocking control in assays to test for specificity of this Fxn antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Frataxin

Target: Frataxin (FXN)

Andere Bezeichnung: Fxn (FXN Produkte)

Synonyme: zgc:158218 antikoerper, LOC100284365 antikoerper, BcDNA:AT09528 antikoerper, CG8971 antikoerper, DFH antikoerper, Dfh antikoerper, Dmel\\CG8971 antikoerper, X25 antikoerper, dfh antikoerper, CyaY antikoerper, FA antikoerper, FARR antikoerper, FRDA antikoerper, RGD1565754 antikoerper, Frda antikoerper, frataxin antikoerper, fxn antikoerper, LOC100284365 antikoerper, TVAG_182150 antikoerper, fh antikoerper, FTX1 antikoerper, FXN antikoerper, Fxn antikoerper

Hintergrund: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1. Synonyms: Polyclonal Fxn antibody, Anti-Fxn antibody, frataxin antibody, FA antibody, FARR antibody, Frda antibody, X25 antibody.

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size