LRP8 Antikörper (Middle Region)
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- Target Alle LRP8 Antikörper anzeigen
- LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LRP8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified
- Immunogen
- Lrp8 antibody was raised in rabbit using the middle region of Lrp8 as the immunogen
- Top Product
- Discover our top product LRP8 Primärantikörper
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- Applikationshinweise
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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Lrp8 Blocking Peptide, catalog no. 33R-1206, is also available for use as a blocking control in assays to test for specificity of this Lrp8 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
- Andere Bezeichnung
- Lrp8 (LRP8 Produkte)
- Synonyme
- LRP8 antikoerper, APOER2 antikoerper, HSZ75190 antikoerper, LRP-8 antikoerper, MCI1 antikoerper, 4932703M08Rik antikoerper, AA921429 antikoerper, AI848122 antikoerper, ApoER2 antikoerper, Lr8b antikoerper, LR8B antikoerper, LDL receptor related protein 8 antikoerper, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antikoerper, LRP8 antikoerper, Lrp8 antikoerper
- Hintergrund
- Lrp8 is the cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Synonyms: Polyclonal Lrp8 antibody, Anti-Lrp8 antibody, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antibody, 4932703M08Rik antibody, AA921429 antibody, AI848122 antibody, Lr8b antibody, apoER2 antibody.
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