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LRP8 Antikörper (Middle Region)

LRP8 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN928054
  • Target Alle LRP8 Antikörper anzeigen
    LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
    Bindungsspezifität
    • 15
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 50
    • 23
    • 20
    • 17
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 47
    • 4
    Kaninchen
    Klonalität
    • 46
    • 5
    Polyklonal
    Konjugat
    • 25
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LRP8 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 25
    • 15
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus
    Aufreinigung
    Purified
    Immunogen
    Lrp8 antibody was raised in rabbit using the middle region of Lrp8 as the immunogen
    Top Product
    Discover our top product LRP8 Primärantikörper
  • Applikationshinweise
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    Lrp8 Blocking Peptide, catalog no. 33R-1206, is also available for use as a blocking control in assays to test for specificity of this Lrp8 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
    Andere Bezeichnung
    Lrp8 (LRP8 Produkte)
    Synonyme
    LRP8 antikoerper, APOER2 antikoerper, HSZ75190 antikoerper, LRP-8 antikoerper, MCI1 antikoerper, 4932703M08Rik antikoerper, AA921429 antikoerper, AI848122 antikoerper, ApoER2 antikoerper, Lr8b antikoerper, LR8B antikoerper, LDL receptor related protein 8 antikoerper, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antikoerper, LRP8 antikoerper, Lrp8 antikoerper
    Hintergrund
    Lrp8 is the cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Synonyms: Polyclonal Lrp8 antibody, Anti-Lrp8 antibody, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antibody, 4932703M08Rik antibody, AA921429 antibody, AI848122 antibody, Lr8b antibody, apoER2 antibody.
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