PHD1 Antikörper (N-Term)

Produktnummer ABIN927508

Produktdetails anti-PHD1 Antikörper

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Zebrafisch (Brachydanio rerio), Huhn, Frosch

Aufreinigung: Purified

Immunogen: EGLN2 antibody was raised in rabbit using the N terminal of EGLN2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

EGLN2 Blocking Peptide, catalog no. 33R-5815, is also available for use as a blocking control in assays to test for specificity of this EGLN2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PHD1

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Andere Bezeichnung: EGLN2 (EGLN2 Produkte)

Synonyme: egln2 antikoerper, phd2 antikoerper, PHD1 antikoerper, 0610011A13Rik antikoerper, C85656 antikoerper, Hif-p4h-1 antikoerper, Ier4 antikoerper, Phd1 antikoerper, SM-20 antikoerper, HIF-PH1 antikoerper, HPH-1 antikoerper, HPH-3 antikoerper, PHD-1 antikoerper, EIT6 antikoerper, HIFPH1 antikoerper, egl-9 family hypoxia-inducible factor 1 antikoerper, egl-9 family hypoxia inducible factor 2 antikoerper, Egl nine homolog 2 antikoerper, egl-9 family hypoxia-inducible factor 2 L homeolog antikoerper, egl-9 family hypoxia-inducible factor 2 antikoerper, egln1 antikoerper, EGLN2 antikoerper, egln2 antikoerper, egln2.L antikoerper, Egln2 antikoerper

Hintergrund: The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. Synonyms: Polyclonal EGLN2 antibody, Anti-EGLN2 antibody, egl nine homolog 2, C. elegans antibody.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis