SH2D1A Antikörper (C-Term)
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- Target Alle SH2D1A Antikörper anzeigen
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SH2D1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Purified
- Immunogen
- SH2 D2 antibody was raised in rabbit using the C terminal of SH2 2 as the immunogen
- Top Product
- Discover our top product SH2D1A Primärantikörper
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- Applikationshinweise
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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SH2D1A Blocking Peptide, catalog no. 33R-10098, is also available for use as a blocking control in assays to test for specificity of this SH2D1A antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- Andere Bezeichnung
- SH2D1A (SH2D1A Produkte)
- Synonyme
- DSHP antikoerper, EBVS antikoerper, IMD5 antikoerper, LYP antikoerper, MTCP1 antikoerper, SAP antikoerper, SAP/SH2D1A antikoerper, XLP antikoerper, XLPD antikoerper, RGD1562408 antikoerper, Gm686 antikoerper, SH2D1A antikoerper, SH2 domain containing 1A antikoerper, SH2D1A antikoerper, Sh2d1a antikoerper
- Hintergrund
- SH2D1A is a protein that plays a major role in the bidirectional stimulation of T and B cells. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in SH2D1A gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Synonyms: Polyclonal SH2D1A antibody, Anti-SH2D1A antibody, SH2 domain protein 1A antibody, DSHP antibody, EBVS antibody, FLJ18687 antibody, FLJ92177 antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, XLP antibody, XLPD antibody.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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