MAFK Antikörper (N-Term)

Produktnummer ABIN925961

Produktdetails anti-MAFK Antikörper

Target: MAFK (Transcription Factor MafK (MAFK))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAFK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Huhn, Frosch, Zebrafisch (Brachydanio rerio), Rind (Kuh)

Immunogen: MAFK antibody was raised in rabbit using the N terminal of MAFK as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MAFK Blocking Peptide, catalog no. 33R-4314, is also available for use as a blocking control in assays to test for specificity of this MAFK antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MAFK

Target: MAFK (Transcription Factor MafK (MAFK))

Andere Bezeichnung: MAFK (MAFK Produkte)

Synonyme: NFE2U antikoerper, P18 antikoerper, AW061068 antikoerper, NF-E2 antikoerper, Nfe2u antikoerper, MAF bZIP transcription factor K antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K antikoerper, Mafk antikoerper, MAFK antikoerper, mafk antikoerper

Hintergrund: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites. Synonyms: Polyclonal MAFK antibody, Anti-MAFK antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K, avian antibody, FLJ32205 antibody, MGC71717 antibody, NFE2U antibody, P18 antibody.