PMP22 Antikörper (PE-Cy5.5)

Produktnummer ABIN911563

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PMP22 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für PMP22 Antikörper (PE-Cy5.5) (ABIN911563)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMP22 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Western Blotting (WB)

Produktdetails anti-PMP22 Antikörper (PE-Cy5.5)

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PMP-22

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Andere Bezeichnung: PMP22

Hintergrund:

Synonyms: DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, PMP22, GAS3

Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

Molekulargewicht: 22kDa

Gen-ID: 5376

UniProt: Q01453