PPARGC1B Antikörper (AA 901-1023) (AbBy Fluor® 350)

Produktnummer ABIN910852

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PPARGC1B in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PPARGC1B Antikörper (AA 901-1023) (AbBy Fluor® 350) (ABIN910852)

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARGC1B Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PPARGC1B Antikörper (AbBy Fluor® 350)

Bindungsspezifität: AA 901-1023

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGC1 beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PPARGC1B

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Andere Bezeichnung: PGC1 beta

Hintergrund:

Synonyms: PERC, peroxisome prolerative activated receptor, gamma, coactivator 1, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC-1beta, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1, Ppargc1b, PRGC2_HUMAN.

Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle.

Molekulargewicht: 113kDa

Gen-ID: 133522

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha