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KLHL13 Antikörper (AA 351-450) (Alexa Fluor 555)

KLHL13 Reaktivität: Zebrafisch (Danio rerio) WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 555
Produktnummer ABIN903885
  • Target Alle KLHL13 Antikörper anzeigen
    KLHL13 (Kelch-Like 13 (KLHL13))
    Bindungsspezifität
    • 14
    • 3
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 17
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Zebrafisch (Danio rerio)
    Wirt
    • 22
    • 9
    Kaninchen
    Klonalität
    • 22
    • 9
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLHL13 Antikörper ist konjugiert mit Alexa Fluor 555
    Applikation
    • 24
    • 12
    • 12
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Zebrafisch (Danio rerio)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KLHL13
    Isotyp
    IgG
    Top Product
    Discover our top product KLHL13 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KLHL13 (Kelch-Like 13 (KLHL13))
    Andere Bezeichnung
    KLHL13 (KLHL13 Produkte)
    Synonyme
    1200009K10Rik antikoerper, AI451128 antikoerper, Bklhd2 antikoerper, D130072F20Rik antikoerper, mKIAA1309 antikoerper, BKLHD2 antikoerper, Kelch-like protein 13 antikoerper, kelch-like 13 antikoerper, kelch like family member 13 antikoerper, kelch like family member 9 antikoerper, kelch-like family member 13 antikoerper, klh13 antikoerper, Klhl13 antikoerper, KLHL13 antikoerper, KLHL9 antikoerper
    Hintergrund

    Synonyms: Kelch-like protein 13, BTB and kelch domain-containing protein 2, KLH13_HUMAN.

    Background: KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.

    Gen-ID
    90293
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