NDUFA13 Antikörper (AA 51-144) (Alexa Fluor 488)

Produktnummer ABIN899740

Produktdetails anti-NDUFA13 Antikörper (Alexa Fluor 488)

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Bindungsspezifität: AA 51-144

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFA13 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRIM19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Andere Bezeichnung: Grim19 (NDUFA13 Produkte)

Synonyme: GRIM-19 antikoerper, Ndufa13 antikoerper, B16.6 antikoerper, CDA016 antikoerper, GRIM19 antikoerper, 2700054G14Rik antikoerper, AU022060 antikoerper, CGI-39 antikoerper, Grim19 antikoerper, RGD1565358 antikoerper, YJEFN3 antikoerper, NADH:ubiquinone oxidoreductase subunit A13 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antikoerper, cell death-regulatory protein GRIM19 antikoerper, GRIM-19 protein antikoerper, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antikoerper, ndufa13 antikoerper, LOC655421 antikoerper, Ndufa13 antikoerper, CpipJ_CPIJ000908 antikoerper, Bm1_18845 antikoerper, ndufa13.L antikoerper, NDUFA13 antikoerper

Hintergrund:

Synonyms: CDA016, Cell death regulatory protein, Cell death regulatory protein GRIM-19, CGI-39, CGI39 protein, CI-B16.6, GRIM-19, GRIM 19, Complex I-B16.6, Gene associated with retinoic and N-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic interferon induced mortality 19 protein, GRIM-19, NADH dehydrogenase ubiquinone 1 alpha subcomplex, 13, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH ubiquinone oxidoreductase B16.6 subunit, Ndufa13.

Background: A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.

Gen-ID: 51079

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling