CCDC70 Antikörper (Alexa Fluor 488)

Produktnummer ABIN888106

Produktdetails anti-CCDC70 Antikörper

Target: CCDC70 (Coiled-Coil Domain Containing 70 (CCDC70))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC70 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC70

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu CCDC70

Target: CCDC70 (Coiled-Coil Domain Containing 70 (CCDC70))

Andere Bezeichnung: Ccdc70 (CCDC70 Produkte)

Synonyme: 1700112P19Rik antikoerper, coiled-coil domain containing 70 antikoerper, CCDC70 antikoerper, THA_1515 antikoerper, Ccdc70 antikoerper

Hintergrund:

Comprising nearly 4 % of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The gene encoding CCDC70 (Coiled-coil domain-containing protein 70), a 233 amino acid secreted protein, exists on human chromosome 13.

Synonyms: CCDC 70, Coiled coil domain containing 70, Coiled coil domain containing protein 70, FLJ25853, CCD70_HUMAN.

Gen-ID: 83446