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CARD14 Antikörper (AA 1-100) (Alexa Fluor 488)

CARD14 Reaktivität: Human, Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN886388
  • Target Alle CARD14 Antikörper anzeigen
    CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 33
    • 20
    • 4
    Human, Maus
    Wirt
    • 29
    • 3
    • 1
    Kaninchen
    Klonalität
    • 31
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CARD14 Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 23
    • 14
    • 12
    • 12
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CARD14
    Isotyp
    IgG
    Top Product
    Discover our top product CARD14 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
    Andere Bezeichnung
    CARD14 (CARD14 Produkte)
    Synonyme
    BIMP2 antikoerper, CARMA2 antikoerper, PRP antikoerper, PSORS2 antikoerper, PSS1 antikoerper, Bimp2 antikoerper, caspase recruitment domain family member 14 antikoerper, caspase recruitment domain family, member 14 antikoerper, CARD14 antikoerper, Card14 antikoerper
    Hintergrund

    Synonyms: Bcl10 interacting MAGUK protein 2, Bimp 2, Bimp2, CARD 14, CARD containing MAGUK 2 protein, CARD containing MAGUK protein 2, Card maguk protein 2, Carma 2, Carma2, Caspase recruitment domain containing protein 14, Caspase recruitment domain family member 14, Caspase recruitment domain protein 14, CAR14_HUMAN.

    Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.

    Gen-ID
    79092
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