ABCB6 Antikörper (AA 401-520) (AbBy Fluor® 647)

Produktnummer ABIN880779

Dieses Anti-ABCB6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ABCB6 in IF (cc) und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für ABCB6 Antikörper (AA 401-520) (AbBy Fluor® 647) (ABIN880779)

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB6 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ABCB6 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 401-520

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Andere Bezeichnung: ABCB6

Hintergrund:

Synonyms: ABC, ABC14, EST45597, ABC 14, ABC-14, ABCB 6, ABCB-6, PRP, UMAT, ABC transporter umat, MTABC3, Mt-ABC transporter 3, umat, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP binding cassette, sub family B MDR/TAP, member 6, P glycoprotein related protein, Abcb6, ABCB6_HUMAN, ATP binding cassette sub family B member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, Mitochondrial ABC transporter 3, mitochondrial, Mt ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, UMAT, Ubiquitously expressed mammalian ABC half transporter.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Gen-ID: 10058

Pathways: Transition Metal Ion Homeostasis