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CENPF Antikörper (AA 551-650)

CENPF Reaktivität: Human ELISA, WB, IHC (p), IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872667
  • Target Alle CENPF Antikörper anzeigen
    CENPF (Centromere Protein F (CENPF))
    Bindungsspezifität
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 551-650
    Reaktivität
    • 26
    • 2
    • 1
    • 1
    Human
    Wirt
    • 22
    • 4
    • 1
    Kaninchen
    Klonalität
    • 23
    • 4
    Polyklonal
    Konjugat
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CENPF Antikörper ist unkonjugiert
    Applikation
    • 12
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CENPF
    Isotyp
    IgG
    Top Product
    Discover our top product CENPF Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CENPF (Centromere Protein F (CENPF))
    Andere Bezeichnung
    CENPF (CENPF Produkte)
    Synonyme
    LOC100222985 antikoerper, 6530404A22Rik antikoerper, AI325968 antikoerper, CENF antikoerper, Lek1 antikoerper, PRO1779 antikoerper, mitosin antikoerper, im:7140452 antikoerper, im:7144238 antikoerper, im:7154719 antikoerper, im:7156761 antikoerper, si:ch211-152h14.2 antikoerper, hcp-1 antikoerper, CMF1 antikoerper, centromere protein F antikoerper, CENPF antikoerper, Cenpf antikoerper, cenpf antikoerper
    Hintergrund

    Synonyms: CENF, hcp-1, PRO1779, Centromere protein F, CENP-F, AH antigen, Kinetochore protein CENPF, Mitosin, CENPF

    Background: Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia.

    Gen-ID
    1063
    UniProt
    P49454
    Pathways
    Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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