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SUFUH Antikörper (pSer342)

SUFUH Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN871409
  • Target Alle SUFUH Antikörper anzeigen
    SUFUH (Suppressor of Fused Homolog (SUFUH))
    Bindungsspezifität
    • 15
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer342
    Reaktivität
    • 43
    • 26
    • 23
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 40
    • 3
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SUFUH Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 13
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    The antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
    Aufreinigung
    Affinity purified
    Immunogen
    Peptide sequence around phosphorylation site of pSer342 (A-P-S (p) -R-K) derived from Human Sufu. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product SUFUH Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Chen, Yue, Xie, Pu, Jin, Cheng: "Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13502-11, (2011) (PubMed).

  • Target
    SUFUH (Suppressor of Fused Homolog (SUFUH))
    Andere Bezeichnung
    Sufu (SUFUH Produkte)
    Synonyme
    CG6054 antikoerper, Dmel\\CG6054 antikoerper, SU(FU) antikoerper, SUFU antikoerper, Su(Fu) antikoerper, SuFu antikoerper, Sufu antikoerper, su(fu) antikoerper, sufu antikoerper, Xsufu antikoerper, sufuh antikoerper, sufuxl antikoerper, PRO1280 antikoerper, SUFUH antikoerper, SUFUXL antikoerper, Su(fu) antikoerper, dre antikoerper, fi39e05 antikoerper, wu:fi39e05 antikoerper, 2810026F04Rik antikoerper, b2b273Clo antikoerper, Suppressor of fused antikoerper, SUFU negative regulator of hedgehog signaling L homeolog antikoerper, SUFU negative regulator of hedgehog signaling antikoerper, suppressor of fused homolog (Drosophila) antikoerper, Su(fu) antikoerper, sufu.L antikoerper, SUFU antikoerper, sufu antikoerper, Sufu antikoerper
    Hintergrund
    SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)
    Molekulargewicht
    54 kDa
    Gen-ID
    51684
    NCBI Accession
    NP_057253
    UniProt
    Q9UMX1
    Pathways
    Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location
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