PPAPDC3 Antikörper (N-Term)

Produktnummer ABIN783832

Produktdetails anti-PPAPDC3 Antikörper

Target: PPAPDC3 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 3 (PPAPDC3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAPDC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography

Immunogen: 19 amino acid peptide from near the amino of terminus human PPAPDC3.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu PPAPDC3

Target: PPAPDC3 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 3 (PPAPDC3))

Andere Bezeichnung: PPAPDC3 (PPAPDC3 Produkte)

Synonyme: MGC147268 antikoerper, im:7142624 antikoerper, zgc:77336 antikoerper, PPAPDC3 antikoerper, DKFZp468F176 antikoerper, C9orf67 antikoerper, NET39 antikoerper, D830019K17Rik antikoerper, RGD1305821 antikoerper, phospholipid phosphatase 7 (inactive) antikoerper, phospholipid phosphatase 7 antikoerper, plpp7 antikoerper, PLPP7 antikoerper, Plpp7 antikoerper

Hintergrund: PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.Synonyms: C9orf67, Phosphatidic acid phosphatase type 2 domain-containing protein 3, Probable lipid phosphate phosphatase PPAPDC3

Gen-ID: 84814

NCBI Accession: NP_116117

UniProt: Q8NBV4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development