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ZIP2 Antikörper (N-Term)

Slc39a2 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783797
  • Target Alle ZIP2 (Slc39a2) Antikörper anzeigen
    ZIP2 (Slc39a2) (Solute Carrier Family 39 (Zinc Transporter), Member 2 (Slc39a2))
    Bindungsspezifität
    • 4
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 6
    Dieser ZIP2 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Zinc transporter ZIP2 / SLC39A2 at N-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the amino terminus of human ZIP2
    Top Product
    Discover our top product Slc39a2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    ZIP2 (Slc39a2) (Solute Carrier Family 39 (Zinc Transporter), Member 2 (Slc39a2))
    Andere Bezeichnung
    Zinc Transporter ZIP2 / SLC39A2 (Slc39a2 Produkte)
    Synonyme
    6A1 antikoerper, ETI-1 antikoerper, ZIP-2 antikoerper, ZIP2 antikoerper, F730005G13Rik antikoerper, Gm1789 antikoerper, Gm289 antikoerper, Zip2 antikoerper, solute carrier family 39 member 2 antikoerper, solute carrier family 39 (zinc transporter), member 2 antikoerper, SLC39A2 antikoerper, Slc39a2 antikoerper
    Hintergrund
    The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.Synonyms: Eti-1, Solute carrier family 39 member 2, ZIP-2, ZIP2, Zrt- and Irt-like protein 2
    Gen-ID
    29986
    NCBI Accession
    NP_055394
    UniProt
    Q9NP94
    Pathways
    Autophagie
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