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KPNA2 Antikörper (N-Term)
KPNA2
Reaktivität: Human, Maus, Ratte
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-KPNA2 Antikörper
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Target
Alle KPNA2 Antikörper anzeigen
KPNA2
(Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
Bindungsspezifität
Alle Epitope für KPNA2 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für KPNA2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für KPNA2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für KPNA2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für KPNA2 Antikörper
Dieser KPNA2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für KPNA2 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody detects KPNA2 / Importin alpha-2 at N-term.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
15 amino acid peptide near the amino terminus of human KPNA2
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Details zu KPNA2
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Target
KPNA2
(Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
Andere Bezeichnung
KPNA2 / Importin alpha-2 (KPNA2 Produkte )
Synonyme
IPOA1 antikoerper, QIP2 antikoerper, RCH1 antikoerper, SRP1alpha antikoerper, ima2 antikoerper, importin antikoerper, 2410044B12Rik antikoerper, PTAC58 antikoerper, Rch1 antikoerper, ipoa1 antikoerper, kpna2 antikoerper, qip2 antikoerper, rch1 antikoerper, srp1alpha antikoerper, hm:zeh0389 antikoerper, hm:zeh0389r antikoerper, zgc:113902 antikoerper, zgc:86945 antikoerper, karyopherin subunit alpha 2 antikoerper, importin subunit alpha-2 antikoerper, Importin subunit alpha-2 antikoerper, karyopherin (importin) alpha 2 antikoerper, karyopherin alpha-2 subunit like L homeolog antikoerper, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) antikoerper, KPNA2 antikoerper, EDI_246290 antikoerper, EDI_335040 antikoerper, ima2 antikoerper, Kpna2 antikoerper, kpna2.L antikoerper, kpna2 antikoerper
Hintergrund
Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind cargo and three intervening nuclear localization sequences (NLSs). It has recently been reported to play an important role in tumorigenesis and tumor progression.Synonyms: Karyopherin alpha-2, RAG cohort protein 1, RCH1, SRP1-alpha
Gen-ID
3838
NCBI Accession
NP_002257
UniProt
P52292
Pathways
M Phase , Protein targeting to Nucleus
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