ZC3HAV1 Antikörper (C-Term)

Produktnummer ABIN783641

Produktdetails anti-ZC3HAV1 Antikörper

Target: ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZC3HAV1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of human ZC3HAV1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ZC3HAV1

Target: ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))

Andere Bezeichnung: ZC3HAV1 (ZC3HAV1 Produkte)

Synonyme: 1200014N16Rik antikoerper, 2900058M19Rik antikoerper, 9130009D18Rik antikoerper, 9830115L13Rik antikoerper, ARTD13 antikoerper, D6Bwg1452e antikoerper, ZAP antikoerper, Zap antikoerper, FLB6421 antikoerper, PARP13 antikoerper, ZC3H2 antikoerper, ZC3HDC2 antikoerper, zinc finger CCCH type, antiviral 1 antikoerper, zinc finger CCCH-type containing, antiviral 1 antikoerper, Zc3hav1 antikoerper, ZC3HAV1 antikoerper

Hintergrund: The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.Synonyms: PRO1677, ZC3HDC2, Zinc finger CCCH domain-containing protein 2, Zinc finger CCCH-type antiviral protein 1, Zinc finger antiviral protein

Gen-ID: 56829

NCBI Accession: NP_064504

UniProt: Q7Z2W4