SMARCA4 Antikörper (N-Term)

Produktnummer ABIN783268

Produktdetails anti-SMARCA4 Antikörper

Target: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Bindungsspezifität: AA 2-14, N-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SMARCA4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody reacts to Global Transcription Activator Snf2l4 (SMARCA4).

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide STPDPPLGGTPRP-C from from the N-terminus of Human SMARCA4 / BRG1 (NP_001122321.1, NP_003063.2, NP_001122317.1, NP_001122318.1, NP_001122319.1, NP_001122320.1). Genename: SMARCA4 .Remarks: Antigen Modification: Amino Acids 2-14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu SMARCA4

Target: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Andere Bezeichnung: SMARCA4 / BRG1 (SMARCA4 Produkte)

Synonyme: SMARCA4 antikoerper, BAF190 antikoerper, BAF190A antikoerper, BRG1 antikoerper, MRD16 antikoerper, RTPS2 antikoerper, SNF2 antikoerper, SNF2L4 antikoerper, SNF2LB antikoerper, SWI2 antikoerper, hSNF2b antikoerper, brg-1 antikoerper, Brg1 antikoerper, HP1-BP72 antikoerper, SNF2beta antikoerper, SW1/SNF antikoerper, b2b692Clo antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antikoerper, SMARCA4 antikoerper, Smarca4 antikoerper

Hintergrund: Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.Synonyms: ATP-dependent helicase SMARCA4, BRG-1 protein, Brahma protein homolog 1, Mitotic growth and transcription activator, Probable global transcription activator SNF2L4, SNF2-beta, SNF2B, SNF2L4, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

Gen-ID: 6597

NCBI Accession: NP_001122316

UniProt: P51532

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance