CR1L Antikörper

Produktnummer ABIN782451

Produktdetails anti-CR1L Antikörper

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CR1L Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Spezifität: Purified Anti-Rat Crry monoclonal antibody (Clone: 5I2) is a rat-specific membrane complement regulator that can inhibit both antibody-induced classical pathway and alternative pathway complement activation. Crry plays a more dominant role than DAF in regulating the alternative pathway of complement and in preventing spontaneous complement damage of rat erythrocytes, whereas DAF and Crry are both expressed and are equally effective in preventing antibody-induced runaway complement activation on rat erythrocytes.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Erythrocytes from a C3 mutated rat

Klon: 512

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CR1L

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Andere Bezeichnung: CR1L / CRRY (CR1L Produkte)

Hintergrund: Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry

Gen-ID: 54243

NCBI Accession: NP_001005265

UniProt: Q63135

Pathways: Komplementsystem