Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HACE1 Antikörper (AA 75-170)

HACE1 Reaktivität: Maus ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN761141
  • Target Alle HACE1 Antikörper anzeigen
    HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-170
    Reaktivität
    • 34
    • 15
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 22
    • 12
    Kaninchen
    Klonalität
    • 23
    • 11
    Polyklonal
    Konjugat
    • 19
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HACE1 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 18
    • 10
    • 9
    • 6
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HACE1
    Isotyp
    IgG
    Top Product
    Discover our top product HACE1 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
    Andere Bezeichnung
    Hace1 (HACE1 Produkte)
    Synonyme
    HACE1 antikoerper, 1700042J16Rik antikoerper, A730034A22Rik antikoerper, BC025474 antikoerper, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 antikoerper, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 L homeolog antikoerper, HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 antikoerper, HACE1 antikoerper, hace1 antikoerper, hace1.L antikoerper, Hace1 antikoerper
    Hintergrund

    Synonyms: E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HACE1, KIAA1320

    Background: E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

    Gen-ID
    57531
    UniProt
    Q8IYU2
Sie sind hier:
Kundenservice