GADD45GIP1 Antikörper (AA 121-222)

Produktnummer ABIN761096

Produktdetails anti-GADD45GIP1 Antikörper

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Bindungsspezifität: AA 121-222

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD45GIP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GADD45GIP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GADD45GIP1

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Andere Bezeichnung: Gadd45gip1 (GADD45GIP1 Produkte)

Synonyme: si:dkey-194e13.6 antikoerper, CKBBP2 antikoerper, CRIF1 antikoerper, PLINP antikoerper, PLINP-1 antikoerper, PRG6 antikoerper, Plinp1 antikoerper, 2310040G17Rik antikoerper, AI425883 antikoerper, Crif1 antikoerper, growth arrest and DNA-damage-inducible, gamma interacting protein 1 antikoerper, GADD45G interacting protein 1 antikoerper, gadd45gip1 antikoerper, GADD45GIP1 antikoerper, Gadd45gip1 antikoerper

Hintergrund:

Synonyms: CKBBP2, CKII beta associating protein, CKII beta binding protein 2, CKII beta-associating protein, CR6 interacting factor 1, CR6-interacting factor 1, CR1, G45IP_HUMAN, Gadd45gip1, growth arrest and DNA damage inducible, gamma interacting protein 1, Growth arrest and DNA damage-inducible proteins-interacting protein 1, p53 responsive gene 6, p53 responsive gene 6 protein, p53-responsive gene 6 protein, Papillomavirus L2 interacting nuclear protein 1, Papillomavirus L2-interacting nuclear protein 1, PLINP 1, PLINP-1, PLINP1, PRG6.

Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.

Gen-ID: 90480