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HSD11B1 Antikörper (AA 201-292)

HSD11B1 Reaktivität: Human, Maus, Ratte, Pferd ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN750913
  • Target Alle HSD11B1 Antikörper anzeigen
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    Bindungsspezifität
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-292
    Reaktivität
    • 51
    • 25
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd
    Wirt
    • 48
    • 6
    • 2
    Kaninchen
    Klonalität
    • 45
    • 11
    Polyklonal
    Konjugat
    • 35
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser HSD11B1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 18
    • 17
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Pferd, Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HSD11B1
    Isotyp
    IgG
    Top Product
    Discover our top product HSD11B1 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Nakata, Umeda, Masuzaki, Sawai: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).

    Xu, Zhao, Lin, Xiang, Wang, Ye, Huang: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).

  • Target
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    Andere Bezeichnung
    HSD11B1/HSD1 (HSD11B1 Produkte)
    Synonyme
    11-DH antikoerper, 11-beta-HSD1 antikoerper, CORTRD2 antikoerper, HDL antikoerper, HSD11 antikoerper, HSD11B antikoerper, HSD11L antikoerper, SDR26C1 antikoerper, hsd11 antikoerper, hsd11b antikoerper, LRRGT00065 antikoerper, hydroxysteroid 11-beta dehydrogenase 1 antikoerper, hydroxysteroid (11-beta) dehydrogenase 1b antikoerper, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog antikoerper, HSD11B1 antikoerper, HSD11B1b antikoerper, hsd11b1.L antikoerper, Hsd11b1 antikoerper
    Hintergrund

    Synonyms: HDL, 11-DH, HSD11, HSD11B, HSD11L, CORTRD2, SDR26C1, 11-beta-HSD1, Corticosteroid 11-beta-dehydrogenase isozyme 1, 11-beta-hydroxysteroid dehydrogenase 1, HSD11B1

    Background: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

    Gen-ID
    3290
    UniProt
    P28845
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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