ERK1 Antikörper (AA 251-358)

Produktnummer ABIN748373

Produktdetails anti-ERK1 Antikörper

Target: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Bindungsspezifität: AA 251-358

Reaktivität: Human, Maus, Ratte, Huhn, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Huhn, Human, Maus, Kaninchen, Ratte

Homologie: Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse ERK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ERK1 Antikörper (ABIN748373)

Zhang, Liu, Wang, Xie, Sheng, Zhang, Yuan, Han, Weng: "Seasonal Expression of Oxytocin and Oxytocin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus)." in: Scientific reports, Vol. 7, Issue 1, pp. 16627, (2018) (PubMed).

Zhao, Han, Hong, Sun: "Adipose differentiation‑related protein knockdown inhibits vascular smooth muscle cell proliferation and migration and attenuates neointima formation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 3079-3086, (2018) (PubMed).

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, (2017) (PubMed).

Xu, Deng, Wang, Chen, Li, Fan: "RKTG overexpression inhibits proliferation and induces apoptosis of human leukemia cells via suppression of the ERK and PI3K/AKT signaling pathways." in: Oncology letters, Vol. 14, Issue 1, pp. 965-970, (2017) (PubMed).

Zheng, Wang, Zou, Jing, Yang, Li, Wang: "Ginsenoside Rb1 improves cardiac function and remodeling in heart failure." in: Experimental animals, Vol. 66, Issue 3, pp. 217-228, (2017) (PubMed).

Li, Wang, Zhou, Zhang, Le, He: "Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells." in: Oncology letters, Vol. 14, Issue 4, pp. 4751-4757, (2017) (PubMed).

Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, (2016) (PubMed).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, (2016) (PubMed).

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, (2016) (PubMed).

Li, Zheng, Su, Wang, Ling, Zou, Zhou: "Activation of the Extracellular Signal-Regulated Kinase Signaling Is Critical for Human Umbilical Cord Mesenchymal Stem Cell Osteogenic Differentiation." in: BioMed research international, Vol. 2016, pp. 3764372, (2016) (PubMed).

Chen, Shi, Li, Deng, Zhang: "Downregulation of MACC1 expression enhances cisplatin sensitivity in SKOV-3/DDP cells." in: Genetics and molecular research : GMR, Vol. 14, Issue 4, pp. 17134-44, (2016) (PubMed).

Wang, Zhao, Guo, Zhang, Pei: "Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124099, (2015) (PubMed).

Wang, Zhai, Guo, Pei, Zhang: "Picroside II has a neuroprotective effect by inhibiting ERK1/2 activation after cerebral ischemic injury in rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).

Chen, Bao, Chen, Burton, Gong, Gu, Mi, Bao: "Mycobacterium tuberculosis PE25/PPE41 protein complex induces activation and maturation of dendritic cells and drives Th2-biased immune responses." in: Medical microbiology and immunology, (2015) (PubMed).

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, (2015) (PubMed).

An, Dang, Shi, Ye, Wu: ""Qufeng Tongluo" acupuncture prevents the progression of glomerulonephritis by decreasing renal sympathetic nerve activity." in: Journal of ethnopharmacology, Vol. 155, Issue 1, pp. 277-84, (2014) (PubMed).

Xu, Guo, Gao, Shi, He, Gao, Zhang: "Acyldepsipeptides inhibit the growth of renal cancer cells through G1 phase cell cycle arrest." in: Biochemical and biophysical research communications, Vol. 438, Issue 3, pp. 468-72, (2013) (PubMed).

Details zu ERK1

Target: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Andere Bezeichnung: ERK1 (MAPK3 Produkte)

Synonyme: ERK-1 antikoerper, ERK1 antikoerper, ERT2 antikoerper, HS44KDAP antikoerper, HUMKER1A antikoerper, P44ERK1 antikoerper, P44MAPK antikoerper, PRKM3 antikoerper, p44-ERK1 antikoerper, p44-MAPK antikoerper, Erk-1 antikoerper, Erk1 antikoerper, Ert2 antikoerper, Esrk1 antikoerper, Mnk1 antikoerper, Mtap2k antikoerper, Prkm3 antikoerper, p44 antikoerper, p44erk1 antikoerper, p44mapk antikoerper, ERK3 antikoerper, ERK6 antikoerper, P38GAMMA antikoerper, PRKM12 antikoerper, SAPK-3 antikoerper, SAPK3 antikoerper, fi06b09 antikoerper, wu:fi06b09 antikoerper, zERK1 antikoerper, Tb08.10J17.940 antikoerper, MAPK1 antikoerper, MNK1 antikoerper, AW123708 antikoerper, Erk6 antikoerper, P38gamma antikoerper, Prkm12 antikoerper, Sapk3 antikoerper, ATMAPK3 antikoerper, ATMPK3 antikoerper, T6D9.4 antikoerper, mitogen-activated protein kinase 3 antikoerper, mitogen-activated protein kinase 3 antikoerper, mitogen-activated protein kinase 12 antikoerper, mitogen activated protein kinase 3 antikoerper, mitogen-activated serine/threonine-protein kinase antikoerper, MAPK3 antikoerper, Mapk3 antikoerper, MAPK12 antikoerper, mapk3 antikoerper, Tc00.1047053509475.10 antikoerper, Tb927.8.3550 antikoerper, Mapk12 antikoerper, CEK1 antikoerper, MPK3 antikoerper

Hintergrund:

Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk, ERK1/2

Background: The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

Gen-ID: 26413

UniProt: P63085

Pathways: MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteine