PKM2 Antikörper (pTyr105)
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- Target Alle PKM2 Antikörper anzeigen
- PKM2 (Pyruvate Kinase M2 (PKM2))
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Bindungsspezifität
- pTyr105
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PKM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human PKM2 around the phosphorylation site of Tyr105
- Isotyp
- IgG
- Top Product
- Discover our top product PKM2 Primärantikörper
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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibodyPKM2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibodyPKM2 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibodyPKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (p), IF (cc), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 121-151), (N-Term) antibodyPKM2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB5870 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibodyPKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15338 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibodyPKM2 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Andere Bezeichnung
- PKM2 (PKM2 Produkte)
- Hintergrund
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Synonyms: Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3, PKM2
Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
- Gen-ID
- 5315
- UniProt
- P14618
- Pathways
- Warburg Effekt
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