AIMP2 Antikörper (AA 201-300)

Produktnummer ABIN741300

Produktdetails anti-AIMP2 Antikörper

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Bindungsspezifität: AA 201-300

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AIMP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-AIMP2 Antikörper (ABIN741300)

Du, Su, Ye, Wang, Huang, Gong: "Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after Inhaled Corticosteroid Withdrawal in COPD Rats." in: The American journal of Chinese medicine, Vol. 44, Issue 5, pp. 1027-41, (2016) (PubMed).

Details zu AIMP2

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Andere Bezeichnung: AIMP2 (AIMP2 Produkte)

Synonyme: jtv1 antikoerper, MGC53242 antikoerper, pro0992 antikoerper, JTV1 antikoerper, JTV-1 antikoerper, P38 antikoerper, AA407136 antikoerper, AA407225 antikoerper, Aimp2(p38) antikoerper, Jtv1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antikoerper, aimp2.L antikoerper, aimp2 antikoerper, AIMP2 antikoerper, Aimp2 antikoerper

Hintergrund:

Synonyms: P38, JTV1, JTV-1, PRO0992, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Multisynthase complex auxiliary component p38, Protein JTV-1, AIMP2

Background: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Gen-ID: 7965

UniProt: Q13155