NR1I2 Antikörper (AA 101-150)

Produktnummer ABIN738816

Produktdetails anti-NR1I2 Antikörper

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Bindungsspezifität: AA 101-150

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1I2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NR1I2

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Andere Bezeichnung: PAR-2 (NR1I2 Produkte)

Synonyme: BXR antikoerper, ONR1 antikoerper, PAR antikoerper, PAR1 antikoerper, PAR2 antikoerper, PARq antikoerper, PRR antikoerper, PXR antikoerper, SAR antikoerper, SXR antikoerper, PXR.1 antikoerper, PXR.2 antikoerper, PXR1 antikoerper, mPXR antikoerper, bxr antikoerper, nr1i2 antikoerper, onr1 antikoerper, xonr1 antikoerper, nuclear receptor subfamily 1 group I member 2 antikoerper, nuclear receptor subfamily 1, group I, member 2 antikoerper, nuclear receptor subfamily 1 group I member 2 S homeolog antikoerper, NR1I2 antikoerper, Nr1i2 antikoerper, nr1i2.S antikoerper, nr1i2 antikoerper

Hintergrund:

Synonyms: PAR2, GPR11, Proteinase-activated receptor 2, PAR-2, Coagulation factor II receptor-like 1, G-protein coupled receptor 11, Thrombin receptor-like 1, F2RL1

Background: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]

Gen-ID: 2150

UniProt: P55085

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway