SP7 Antikörper (AA 331-431)

Produktnummer ABIN737811

Produktdetails anti-SP7 Antikörper

Target: SP7 (Sp7 Transcription Factor (SP7))

Bindungsspezifität: AA 331-431

Reaktivität: Human, Maus, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Kaninchen

Homologie: Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Osterix

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SP7 Antikörper (ABIN737811)

Li, Xu, Xing, Qian, Chen, Gu, Guo, Lai, Zhao, Li, Wang, Wang, Deng: "A Conditional Knockout Mouse Model Reveals a Critical Role of PKD1 in Osteoblast Differentiation and Bone Development." in: Scientific reports, Vol. 7, pp. 40505, (2017) (PubMed).

Qian, Yan, Bai, Chen, Zhang, Yao, Xia: "Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells." in: Biomedicine & pharmacotherapy, Vol. 90, pp. 492-499, (2017) (PubMed).

Agarwal, Loder, Cholok, Peterson, Li, Fireman, Breuler, Hsieh, Ranganathan, Hwang, Drake, Li, Chan, Longaker, Levi: "Local and Circulating Endothelial Cells Undergo Endothelial to Mesenchymal Transition (EndMT) in Response to Musculoskeletal Injury." in: Scientific reports, Vol. 6, pp. 32514, (2016) (PubMed).

Tang, Tan, Ni, Wang, Zhu, Fan, Chen, Yang, Zhang: "Comparison of ectopic bone formation process induced by four calcium phosphate ceramics in mice." in: Materials science & engineering. C, Materials for biological applications, Vol. 70, Issue Pt 2, pp. 1000-1010, (2016) (PubMed).

Agarwal, Loder, Sorkin, Li, Shrestha, Zhao, Mishina, James, Levi: "Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 6, pp. 1692-701, (2016) (PubMed).

Wang, He, Liu, Liu, Zhou, Hao, Sun, Wang: "Synergistic effects of overexpression of BMP‑2 and TGF‑β3 on osteogenic differentiation of bone marrow mesenchymal stem cells." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5514-5520, (2016) (PubMed).

Rajshankar, Wang, McCulloch: "Osteogenesis requires FAK-dependent collagen synthesis by fibroblasts and osteoblasts." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 3, pp. 937-953, (2016) (PubMed).

Ranganathan, Agarwal, Cholok, Loder, Li, Sung Hsieh, Wang, Buchman, Levi: "The role of the adaptive immune system in burn-induced heterotopic ossification and mesenchymal cell osteogenic differentiation." in: The Journal of surgical research, Vol. 206, Issue 1, pp. 53-61, (2016) (PubMed).

Kishi, Fujihara, Kawaguchi, Yamada, Nakayama, Yamamoto, Fujihara, Hamada, Satomura, Masutani: "PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway." in: International journal of molecular sciences, Vol. 16, Issue 10, pp. 24820-38, (2015) (PubMed).

Chen, Lazarenko, Zhang, Blackburn, Ronis, Badger: "Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 5, pp. 1043-53, (2014) (PubMed).

Dong, Ge, Zhang, Fu, Zhang, Cheng, Jiang: "Phenotypic characterization of craniofacial bone marrow stromal cells: unique properties of enhanced osteogenesis, cell recruitment, autophagy, and apoptosis resistance." in: Cell and tissue research, Vol. 358, Issue 1, pp. 165-75, (2014) (PubMed).

Details zu SP7

Target: SP7 (Sp7 Transcription Factor (SP7))

Andere Bezeichnung: Osterix (SP7 Produkte)

Synonyme: BBBG1 antikoerper, FXY antikoerper, GBBB1 antikoerper, MIDIN antikoerper, OGS1 antikoerper, OS antikoerper, OSX antikoerper, RNF59 antikoerper, TRIM18 antikoerper, XPRF antikoerper, ZNFXY antikoerper, OI11 antikoerper, OI12 antikoerper, osterix antikoerper, Osx antikoerper, osx antikoerper, SP7 antikoerper, sp7 antikoerper, 6430578P22Rik antikoerper, C22 antikoerper, midline 1 antikoerper, Sp7 transcription factor antikoerper, uncharacterized LOC100063836 antikoerper, Sp7 transcription factor L homeolog antikoerper, Sp7 transcription factor 7 antikoerper, MID1 antikoerper, SP7 antikoerper, Sp7 antikoerper, sp7 antikoerper, LOC100063836 antikoerper, sp7.L antikoerper

Hintergrund:

Synonyms: OSX, OI11, OI12, osterix, Transcription factor Sp7, Zinc finger protein osterix, SP7

Background: Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity).

Gen-ID: 121340

UniProt: Q8TDD2