VCAM1 Antikörper (Vascular Cell Adhesion Molecule 1) (AA 721-739)

Details for Product anti-VCAM1 Antibody No. ABIN729838
Antigen
  • CD106
  • INCAM-100
  • Vcam-1
  • VCAM1B
  • fi76d06
  • wu:fi76d06
  • zgc:158875
  • VCAM1
  • vascular cell adhesion molecule 1
  • vascular cell adhesion molecule 1b
  • VCAM1
  • Vcam1
  • vcam1b
  • VCAM-1
Epitop
AA 721-739
21
14
14
11
10
8
7
5
5
5
5
5
5
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Kaninchen, Ratte (Rattus)
454
187
95
32
11
9
8
8
3
Wirt
Kaninchen
332
178
93
16
13
8
Klonalität
Polyklonal
Konjugat
Dieser VCAM1 Antikörper ist unkonjugiert
67
53
52
15
12
9
9
6
5
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
341
235
205
156
138
103
59
46
41
26
26
23
17
13
10
5
3
3
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human VCAM-1
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere VCAM1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung VCAM1 (VCAM1 Antibody Abstract)
Hintergrund

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

Subcellular location: Cytoplasm

Synonyms: CD16, INCAM-1, Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, VCAM1, L1CAM

Gen-ID 7412
UniProt P19320
Pathways Carbohydrate Homeostasis
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 721-739) antibody (ABIN729838) Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-VCAM-1/...
Immunohistochemistry (IHC) image for anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 721-739) antibody (ABIN729838) Formalin-fixed and paraffin embedded rabbit brain carcinoma labeled with Anti-VCAM-1/...
Flow Cytometry (FACS) image for anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 721-739) antibody (ABIN729838) Mouse splenocytes probed with Rabbit Anti-VCAM1 Polyclonal Antibody, PE-Cy5.5 Conjuga...
Western Blotting (WB) image for anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 721-739) antibody (ABIN729838) Lane 1: mouse heart lysates probed with Rabbit Anti-VCAM1 Polyclonal Antibody, Unconj...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 721-739) antibody (ABIN729838) Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-VCAM-1/...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 721-739) antibody (ABIN729838) Formalin-fixed and paraffin embedded rabbit brain carcinoma labeled with Anti-VCAM-1/...
Produkt verwendet in: Kim, Lee, Yeon, Park, Yang: "Effects of silk fibroin in murine dry eye." in: Scientific reports, Vol. 7, pp. 44364, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: eye

Bartko, Dal-Bianco, Guerrero, Beaudoin, Szymanski, Kim, Seybolt, Handschumacher, Sullivan, Garcia, Titus, Wylie-Sears, Irvin, Messas, Hagège, Carpentier, Aikawa, Bischoff, Levine: "Effect of Losartan on Mitral Valve Changes After Myocardial Infarction." in: Journal of the American College of Cardiology, Vol. 70, Issue 10, pp. 1232-1244, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

Vendrov, Stevenson, Alahari, Pan, Wickline, Madamanchi, Runge: "Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice." in: Journal of the American Heart Association, Vol. 6, Issue 11, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: heart

Tang, Ni, Cai, Ding, Liu, Zhang et al.: "Renoprotective effects of berberine and its potential effect on the expression of β-arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic ..." in: Journal of diabetes, Vol. 8, Issue 5, pp. 693-700, 2016 (PubMed).

Lozhkin, Vendrov, Pan, Wickline, Madamanchi, Runge: "NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis." in: Journal of molecular and cellular cardiology, Vol. 102, pp. 10-21, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: aortic root

Mu, Chen, Gong, Zheng, Xing: "Expression of vascular cell adhesion molecule-1 in the aortic tissues of atherosclerotic patients and the associated clinical implications." in: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 423-428, 2015 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human). Weitere Details: Sample: renal artery tissues

Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: "Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells." in: PLoS ONE, Vol. 9, Issue 11, pp. e111390, 2014 (PubMed).

Ma, Niu, Sun, Wang, Luo, Zhang, Wang: "Inflammatory responses induced by fluoride and arsenic at toxic concentration in rabbit aorta." in: Archives of toxicology, Vol. 86, Issue 6, pp. 849-56, 2012 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rabbit). Weitere Details: Sample: heart

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