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CD31 Antikörper (AA 681-738)

PECAM1 Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh) FACS, WB, ELISA, IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN726140
  • Target Alle CD31 (PECAM1) Antikörper anzeigen
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Bindungsspezifität
    • 18
    • 16
    • 15
    • 12
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 681-738
    Reaktivität
    • 274
    • 141
    • 71
    • 58
    • 41
    • 28
    • 22
    • 17
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh)
    Wirt
    • 159
    • 147
    • 48
    • 7
    • 3
    • 2
    Kaninchen
    Klonalität
    • 233
    • 132
    • 1
    Polyklonal
    Konjugat
    • 156
    • 33
    • 33
    • 24
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD31 Antikörper ist unkonjugiert
    Applikation
    • 227
    • 185
    • 97
    • 88
    • 62
    • 37
    • 36
    • 33
    • 25
    • 25
    • 22
    • 15
    • 13
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Rind (Kuh), Human, Maus, Schwein, Kaninchen, Ratte
    Homologie
    Dog,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CD31
    Isotyp
    IgG
    Top Product
    Discover our top product PECAM1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Kong, Lee, Youm, Kim, Lee, Suh, Kim: "Effect of treatment with angiopoietin-2 and vascular endothelial growth factor on the quality of xenografted bovine ovarian tissue in mice." in: PLoS ONE, Vol. 12, Issue 9, pp. e0184546, (2018) (PubMed).

    Brumm, Nunez, Doroudchi, Kawaguchi, Duan, Pellegrini, Lam, Carmichael, Deb, Hinman: "Astrocytes Can Adopt Endothelial Cell Fates in a p53-Dependent Manner." in: Molecular neurobiology, Vol. 54, Issue 6, pp. 4584-4596, (2018) (PubMed).

    Lee, Lee, Lee, Choi, Yang: "Chondrocyte-derived extracellular matrix suppresses pathogenesis of human pterygium epithelial cells by blocking the NF-κB signaling pathways." in: Molecular vision, Vol. 22, pp. 1490-1502, (2018) (PubMed).

    Wang, Chen, Wang, Shi, Wang, Zhang, Gao, Li, Qi, An, Chen: "Targeting neurokinin-3 receptor: a novel anti-angiogenesis strategy for cancer treatment." in: Oncotarget, Vol. 8, Issue 25, pp. 40713-40723, (2018) (PubMed).

    Wang, Chen, Ke, Li: "Ghrelin inhibits atherosclerotic plaque angiogenesis and promotes plaque stability in a rabbit atherosclerotic model." in: Peptides, Vol. 90, pp. 17-26, (2017) (PubMed).

    Korkmaz, Ulrich, Vogels, de Wit, van Zuijlen, Krijnen, Niessen: "Neutrophil extracellular traps coincide with a pro-coagulant status of microcirculatory endothelium in burn wounds." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Vol. 25, Issue 4, pp. 609-617, (2017) (PubMed).

    Wu, Zhang, Ye, Shen, Liu, Hu, Li, Wu, Chen, Zhou: "Overexpression and correlation of HIF-2α, VEGFA and EphA2 in residual hepatocellular carcinoma following high-intensity focused ultrasound treatment: Implications for tumor recurrence and progression." in: Experimental and therapeutic medicine, Vol. 13, Issue 6, pp. 3529-3534, (2017) (PubMed).

    Yang, Pei, Wang, Jin, Yu, Zhou, Zhang, Zhang, Lin: "Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73." in: BMC cancer, Vol. 17, Issue 1, pp. 255, (2017) (PubMed).

    Schuerlein, Schwarz, Krziminski, Gätzner, Hoppensack, Schwedhelm, Schweinlin, Walles, Hansmann: "A versatile modular bioreactor platform for Tissue Engineering." in: Biotechnology journal, (2016) (PubMed).

    Struecker, Hillebrandt, Raschzok, Jöhrens, Butter, Tang, Andreou, Napierala, Reutzel-Selke, Denecke, Pratschke, Sauer: "Implantation of a Tissue-Engineered Neo-Bile Duct in Domestic Pigs." in: European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes, Vol. 56, Issue 1-2, pp. 61-75, (2016) (PubMed).

    Ji, Zhang, Chen, Che, Zhou, Wang: "Sodium humate accelerates cutaneous wound healing by activating TGF-β/Smads signaling pathway in rats." in: Acta pharmaceutica Sinica. B, Vol. 6, Issue 2, pp. 132-40, (2016) (PubMed).

    Pei, Yang, Wang, Zhang, Zhou, Zhang, Lin: "Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2." in: BMC cancer, Vol. 15, pp. 965, (2016) (PubMed).

    Xiang, Zheng, Zhou, Qiao, Tran, Pu, Li, Kong, Kouzani, Lin, Liu, Li, Shigdar, Duan: "Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors." in: Theranostics, Vol. 5, Issue 10, pp. 1083-97, (2015) (PubMed).

    Karaca, Hulya Uz, Karabacak, Karaboga, Demirtas, Cagatay Cicek: "Effects of hyperthyroidism on expression of vascular endothelial growth factor (VEGF) and apoptosis in fetal adrenal glands." in: European journal of histochemistry : EJH, Vol. 59, Issue 4, pp. 2560, (2015) (PubMed).

    Sun, Ni, Sun, Cai, Yu, Wang, Nie, Sun, Ni, Cao: "Adipose-Derived Stem Cells Alleviate Radiation-Induced Muscular Fibrosis by Suppressing the Expression of TGF-β1." in: Stem cells international, Vol. 2016, pp. 5638204, (2015) (PubMed).

    Lee, Lee, Yang: "Effect of porcine chondrocyte-derived extracellular matrix on the pterygium in mouse model." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 252, Issue 4, pp. 609-18, (2014) (PubMed).

    Liu, Xue, Li, Zhang, Fu, Feng, Chen, Xu: "Amelioration of stroke-induced neurological deficiency by lyophilized powder of catapol and puerarin." in: International journal of biological sciences, Vol. 10, Issue 4, pp. 448-56, (2014) (PubMed).

    Choi, Choi, Lee, Song, Park, Yang, Min: "Inhibition of blood vessel formation by a chondrocyte-derived extracellular matrix." in: Biomaterials, Vol. 35, Issue 22, pp. 5711-20, (2014) (PubMed).

    Lee, Lee, Kim, Yang: "Anti-neovascular effect of chondrocyte-derived extracellular matrix on corneal alkaline burns in rabbits." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 252, Issue 6, pp. 951-61, (2014) (PubMed).

  • Target
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Andere Bezeichnung
    CD31 (PECAM1 Produkte)
    Synonyme
    CD31 antikoerper, CD31/EndoCAM antikoerper, GPIIA' antikoerper, PECA1 antikoerper, PECAM-1 antikoerper, endoCAM antikoerper, C85791 antikoerper, Cd31 antikoerper, Pecam antikoerper, platelet/endothelial cell adhesion molecule 1 antikoerper, platelet and endothelial cell adhesion molecule 1 antikoerper, pecam1 antikoerper, PECAM1 antikoerper, Pecam1 antikoerper
    Hintergrund

    Synonyms: CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM, Platelet endothelial cell adhesion molecule, PECAM1

    Background: Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

    Gen-ID
    5175
    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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