HSP90AB1 Antikörper (AA 635-724)

Produktnummer ABIN725495

Produktdetails anti-HSP90AB1 Antikörper

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Bindungsspezifität: AA 635-724

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSP90AB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP90 beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-HSP90AB1 Antikörper (ABIN725495)

Bozok Cetintas, Acikgoz, Yigitturk, Demir, Oktem, Tezcanli Kaymaz, Oltulu, Aktug: "Effects of flavopiridol on critical regulation pathways of CD133high/CD44high lung cancer stem cells." in: Medicine, Vol. 95, Issue 43, pp. e5150, (2016) (PubMed).

Mori, Akita, Tanida, Ishida, Toda, Inoue, Yashiro, Sawada, Hirakawa, Nakada et al.: "MUC1 protein induces urokinase-type plasminogen activator (uPA) by forming a complex with NF-κB p65 transcription factor and binding to the uPA promoter, leading to enhanced invasiveness of cancer ..." in: The Journal of biological chemistry, Vol. 289, Issue 51, pp. 35193-204, (2015) (PubMed).

Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: "Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost." in: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 683-93, (2013) (PubMed).

Details zu HSP90AB1

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Andere Bezeichnung: HSP90 beta (HSP90AB1 Produkte)

Synonyme: D6S182 antikoerper, HSP84 antikoerper, HSP90B antikoerper, HSPC2 antikoerper, HSPCB antikoerper, GRP94 antikoerper, TRA1 antikoerper, hsp90b antikoerper, 90kDa antikoerper, AL022974 antikoerper, C81438 antikoerper, Hsp84 antikoerper, Hsp84-1 antikoerper, Hsp90 antikoerper, Hspcb antikoerper, Hsp70 antikoerper, Hsp70-1 antikoerper, Hsp70.1 antikoerper, hsp68 antikoerper, HSP90-BETA antikoerper, hsp90beta antikoerper, wu:fa29f01 antikoerper, wu:fa91e11 antikoerper, wu:fd59e11 antikoerper, wu:gcd22h07 antikoerper, HSP90 antikoerper, heat shock protein 90 alpha family class B member 1 antikoerper, heat shock protein 90 beta family member 1 antikoerper, Heat Shock Protein 90, endoplasmic reticulum antikoerper, heat shock protein 90B antikoerper, heat shock protein 90 alpha (cytosolic), class B member 1 antikoerper, heat shock protein 1B antikoerper, heat shock protein 90kDa alpha family class B member 1 S homeolog antikoerper, heat shock protein 90, alpha (cytosolic), class B member 1 antikoerper, HSP90AB1 antikoerper, HSP90B1 antikoerper, HSP90B antikoerper, hsp90ab1 antikoerper, Hsp90ab1 antikoerper, Hspa1b antikoerper, hsp90ab1.S antikoerper

Hintergrund:

Synonyms: HSP84, HSPC2, HSPCB, D6S182, HSP9B, Heat shock protein HSP 9-beta, HSP 9, Heat shock 84 kDa, HSP 84, HSP9AB1

Background: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Gen-ID: 3326

UniProt: P08238

Pathways: Regulation of Cell Size