ACTH 7-23 Antikörper

Produktnummer ABIN723485

Produktdetails

Target: ACTH 7-23

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACTH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen

Jussila, Huotari-Orava, Ylianttila, Partonen, Snellman: "Narrow-band ultraviolet B radiation induces the expression of β-endorphin in human skin in vivo." in: Journal of photochemistry and photobiology. B, Biology, Vol. 155, pp. 104-8, (2016) (PubMed).

Zhou, Wei, Kuang, Luo, Ma, Zeng, Wang, Liu, Gong, Wang, Lei, Wang, Zeng, Wang, He, Yuan, Dai, He, Xing: "A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation." in: Journal of cellular and molecular medicine, Vol. 21, Issue 4, pp. 802-815, (2016) (PubMed).

Antigendetails

Target: ACTH 7-23

Hintergrund:

Synonyms: Adrenocorticotropic hormone, Adrenocorticotropin, Adrenocorticotropin Hormone, Alpha Melanocyte Stimulating Hormone, Beta Endorphin, Beta Lipotropin, Beta Melanocyte Stimulating Hormone, CLIP, Corticotropin, Corticotropin Like Intermediary Peptide, Corticotropin lipotropin precursor, Lipotropin Beta, Lipotropin Gamma, LPH, Melanotropin Alpha, Met Enkephalin, MSH, NPP, POC, POMC, Pro opiomelanocortin, Proopiomelanocortin.

Background: ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.

Gen-ID: 5443

UniProt: P01189