MORG1 Antikörper (AA 201-315)

Produktnummer ABIN720475

Produktdetails anti-MORG1 Antikörper

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Bindungsspezifität: AA 201-315

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MORG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAPK organizer 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MORG1

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Andere Bezeichnung: MAPK organizer 1 (wdr83 Produkte)

Synonyme: MORG1 antikoerper, 1500041N16Rik antikoerper, Morg1 antikoerper, RGD1306947 antikoerper, morg1 antikoerper, MAPK organizer 1 antikoerper, wu:fj29g04 antikoerper, zgc:92654 antikoerper, WD repeat domain 83 antikoerper, WD repeat domain containing 83 antikoerper, WD repeat domain 83 L homeolog antikoerper, WDR83 antikoerper, Wdr83 antikoerper, wdr83.L antikoerper, wdr83 antikoerper

Hintergrund:

Synonyms: MORG1, WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83

Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Gen-ID: 84292

UniProt: Q9BRX9